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Human Dimethyladenosine transferase 1 mitochondrial (aa 1-346)

CGI-75 Swiss Prot#

Q8WVM0

CGI-75 Protein names

Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (mtTFB1) (h-mtTFB1) (h-mtTFB) (hTFB1M)

CGI-75 Gene names

TFB1M CGI-75

Organism

Human

CGI-75 Entry name

TFB1M_HUMAN

CGI-75 Codon optimized cDNA(gene) Clone

CGI-75 Cat #

RPS0896

Tag

CGI-75 contains A 6x histidine tag

CGI-75 Formulation

Liquid

CGI-75 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CGI-75 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CGI-75 Protein

CGI-75 Cat #

PS0896

CGI-75 Source

recombinant

CGI-75 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CGI-75 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CGI-75 Activity

N/A

Tag

CGI-75 Contains A 6x histidine tag

CGI-75 Formulation

Liquid

CGI-75 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CGI-75 family

Methyltransferase superfamily, rRNA adenine N(6)-methyltransferase family, KsgA subfamily

CGI-75 Subcellular locations

Mitochondrion.

CGI-75 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.

CGI-75 Sequence

DDBJ

EMBL

GenBank

CGI-75 3D structure

ModBase

CGI-75 interaction

STRING

CGI-75 Proteomic

PRIDE

CGI-75 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CGI-75 Organism specific

CTD

MGI

CGI-75 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CGI-75 Gene expression

Bgee

ArrayExpress

Genevestigator

CGI-75 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY