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Human Transcriptional enhancer factor TEF-3 (aa 1-434)

RTEF1 Swiss Prot#

Q15561

RTEF1 Protein names

Transcriptional enhancer factor TEF-3 (TEA domain family member 4) (TEAD-4) (Transcription factor RTEF-1) (Transcription factor 13-like 1)

RTEF1 Gene names

TEAD4 RTEF1 TCF13L1 TEF3

Organism

Human

RTEF1 Entry name

TEAD4_HUMAN

RTEF1 Codon optimized cDNA(gene) Clone

RTEF1 Cat #

RPS0887

Tag

RTEF1 contains A 6x histidine tag

RTEF1 Formulation

Liquid

RTEF1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

RTEF1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant RTEF1 Protein

RTEF1 Cat #

PS0887

RTEF1 Source

recombinant

RTEF1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

RTEF1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

RTEF1 Activity

N/A

Tag

RTEF1 Contains A 6x histidine tag

RTEF1 Formulation

Liquid

RTEF1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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RTEF1 family

-

RTEF1 Subcellular locations

Nucleus.

RTEF1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.

RTEF1 Sequence

DDBJ

EMBL

GenBank

RTEF1 3D structure

ModBase

RTEF1 interaction

STRING

RTEF1 Proteomic

PRIDE

RTEF1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

RTEF1 Organism specific

CTD

MGI

RTEF1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

RTEF1 Gene expression

Bgee

ArrayExpress

Genevestigator

RTEF1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY