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Human Transcriptional activator protein Pur-beta (aa 1-312)

PURB Swiss Prot#

Q96QR8

PURB Protein names

Transcriptional activator protein Pur-beta (Purine-rich element-binding protein B)

PURB Gene names

PURB

Organism

Human

PURB Entry name

PURB_HUMAN

PURB Codon optimized cDNA(gene) Clone

PURB Cat #

RPS0684

Tag

PURB contains A 6x histidine tag

PURB Formulation

Liquid

PURB Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PURB Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PURB Protein

PURB Cat #

PS0684

PURB Source

recombinant

PURB Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PURB Purity

>90%, as determined by SDS-PAGE under reducing conditions

PURB Activity

N/A

Tag

PURB Contains A 6x histidine tag

PURB Formulation

Liquid

PURB Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PURB family

PUR DNA-binding protein family

PURB Subcellular locations

Nucleus.

PURB FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity).

PURB Sequence

DDBJ

EMBL

GenBank

PURB 3D structure

ModBase

PURB interaction

STRING

PURB Proteomic

PRIDE

PURB Genome annotation

Ensembl

GeneID

KEGG

UCSC

PURB Organism specific

CTD

MGI

PURB Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PURB Gene expression

Bgee

ArrayExpress

Genevestigator

PURB Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY