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Human Polyglutamine-binding protein 1 (aa 1-265)

NPW38 Swiss Prot#

O60828

NPW38 Protein names

Polyglutamine-binding protein 1 (PQBP-1) (Polyglutamine tract-binding protein 1) (38 kDa nuclear protein containing a WW domain) (Npw38)

NPW38 Gene names

PQBP1 NPW38 JM26

Organism

Human

NPW38 Entry name

PQBP1_HUMAN

NPW38 Codon optimized cDNA(gene) Clone

NPW38 Cat #

RPS0662

Tag

NPW38 contains A 6x histidine tag

NPW38 Formulation

Liquid

NPW38 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

NPW38 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant NPW38 Protein

NPW38 Cat #

PS0662

NPW38 Source

recombinant

NPW38 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

NPW38 Purity

>90%, as determined by SDS-PAGE under reducing conditions

NPW38 Activity

N/A

Tag

NPW38 Contains A 6x histidine tag

NPW38 Formulation

Liquid

NPW38 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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NPW38 family

-

NPW38 Subcellular locations

Nucleus.

NPW38 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.

NPW38 Sequence

DDBJ

EMBL

GenBank

NPW38 3D structure

ModBase

NPW38 interaction

STRING

NPW38 Proteomic

PRIDE

NPW38 Genome annotation

Ensembl

GeneID

KEGG

UCSC

NPW38 Organism specific

CTD

MGI

NPW38 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NPW38 Gene expression

Bgee

ArrayExpress

Genevestigator

NPW38 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY