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Human Paired box protein Pax-6 (aa 1-422)

AN2 Swiss Prot#

P26367

AN2 Protein names

Paired box protein Pax-6 (Oculorhombin) (Aniridia type II protein)

AN2 Gene names

PAX6 AN2

Organism

Human

AN2 Entry name

PAX6_HUMAN

AN2 Codon optimized cDNA(gene) Clone

AN2 Cat #

RPS0610

Tag

AN2 contains A 6x histidine tag

AN2 Formulation

Liquid

AN2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

AN2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant AN2 Protein

AN2 Cat #

PS0610

AN2 Source

recombinant

AN2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

AN2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

AN2 Activity

N/A

Tag

AN2 Contains A 6x histidine tag

AN2 Formulation

Liquid

AN2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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AN2 family

Paired homeobox family

AN2 Subcellular locations

Nucleus.

AN2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.

AN2 Sequence

DDBJ

EMBL

GenBank

AN2 3D structure

ModBase

AN2 interaction

STRING

AN2 Proteomic

PRIDE

AN2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

AN2 Organism specific

CTD

MGI

AN2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

AN2 Gene expression

Bgee

ArrayExpress

Genevestigator

AN2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY