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Human Mediator RNA polymerase II transcription subunit 27 (aa 1-311)

CRSP34 Swiss Prot#

Q6P2C8

CRSP34 Protein names

Mediator of RNA polymerase II transcription subunit 27 (Mediator complex subunit 27) (Cofactor required for Sp1 transcriptional activation subunit 8) (CRSP complex subunit 8) (Transcriptional coactivator CRSP34) (P37 TRAP/SMCC/PC2 subunit)

CRSP34 Gene names

MED27 CRSP34 CRSP8

Organism

Human

CRSP34 Entry name

MED27_HUMAN

CRSP34 Codon optimized cDNA(gene) Clone

CRSP34 Cat #

RPS0484

Tag

CRSP34 contains A 6x histidine tag

CRSP34 Formulation

Liquid

CRSP34 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CRSP34 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CRSP34 Protein

CRSP34 Cat #

PS0484

CRSP34 Source

recombinant

CRSP34 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CRSP34 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CRSP34 Activity

N/A

Tag

CRSP34 Contains A 6x histidine tag

CRSP34 Formulation

Liquid

CRSP34 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CRSP34 family

Mediator complex subunit 27 family

CRSP34 Subcellular locations

Nucleus.

CRSP34 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

CRSP34 Sequence

DDBJ

EMBL

GenBank

CRSP34 3D structure

ModBase

CRSP34 interaction

STRING

CRSP34 Proteomic

PRIDE

CRSP34 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CRSP34 Organism specific

CTD

MGI

CRSP34 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CRSP34 Gene expression

Bgee

ArrayExpress

Genevestigator

CRSP34 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY