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Human Iroquois-class homeodomain protein IRX-3 (aa 1-501)

IRXB1 Swiss Prot#

P78415

IRXB1 Protein names

Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1)

IRXB1 Gene names

IRX3 IRXB1

Organism

Human

IRXB1 Entry name

IRX3_HUMAN

IRXB1 Codon optimized cDNA(gene) Clone

IRXB1 Cat #

RPS0392

Tag

IRXB1 contains A 6x histidine tag

IRXB1 Formulation

Liquid

IRXB1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

IRXB1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant IRXB1 Protein

IRXB1 Cat #

PS0392

IRXB1 Source

recombinant

IRXB1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

IRXB1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

IRXB1 Activity

N/A

Tag

IRXB1 Contains A 6x histidine tag

IRXB1 Formulation

Liquid

IRXB1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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IRXB1 family

TALE/IRO homeobox family

IRXB1 Subcellular locations

Nucleus.

IRXB1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity).

IRXB1 Sequence

DDBJ

EMBL

GenBank

IRXB1 3D structure

ModBase

IRXB1 interaction

STRING

IRXB1 Proteomic

PRIDE

IRXB1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

IRXB1 Organism specific

CTD

MGI

IRXB1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

IRXB1 Gene expression

Bgee

ArrayExpress

Genevestigator

IRXB1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY