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Human Interferon regulatory factor 9 (aa 1-393)

ISGF3G Swiss Prot#

Q00978

ISGF3G Protein names

Interferon regulatory factor 9 (IRF-9) (Transcriptional regulator ISGF3 subunit gamma) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF-3 gamma) (ISGF3 p48 subunit)

ISGF3G Gene names

IRF9 ISGF3G

Organism

Human

ISGF3G Entry name

IRF9_HUMAN

ISGF3G Codon optimized cDNA(gene) Clone

ISGF3G Cat #

RPS0389

Tag

ISGF3G contains A 6x histidine tag

ISGF3G Formulation

Liquid

ISGF3G Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ISGF3G Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ISGF3G Protein

ISGF3G Cat #

PS0389

ISGF3G Source

recombinant

ISGF3G Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ISGF3G Purity

>90%, as determined by SDS-PAGE under reducing conditions

ISGF3G Activity

N/A

Tag

ISGF3G Contains A 6x histidine tag

ISGF3G Formulation

Liquid

ISGF3G Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ISGF3G family

IRF family

ISGF3G Subcellular locations

Cytoplasm. Nucleus.

ISGF3G FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

ISGF3G Sequence

DDBJ

EMBL

GenBank

ISGF3G 3D structure

ModBase

ISGF3G interaction

STRING

ISGF3G Proteomic

PRIDE

ISGF3G Genome annotation

Ensembl

GeneID

KEGG

UCSC

ISGF3G Organism specific

CTD

MGI

ISGF3G Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ISGF3G Gene expression

Bgee

ArrayExpress

Genevestigator

ISGF3G Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY