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Human Histone deacetylase 8 (aa 1-377)
HDAC8 Swiss Prot#
Q9BY41
HDAC8 Protein names
Histone deacetylase 8 (HD8) (EC 3.5.1.98)
HDAC8 Gene names
HDAC8 HDACL1 CDA07
Organism
Human
HDAC8 Entry name
HDAC8_HUMAN
HDAC8 Codon optimized cDNA(gene) Clone
HDAC8 Cat #
RPS0293
Tag
HDAC8 contains A 6x histidine tag
HDAC8 Formulation
Liquid
HDAC8 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
HDAC8 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant HDAC8 Protein
HDAC8 Cat #
PS0293
HDAC8 Source
recombinant
HDAC8 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
HDAC8 Purity
>90%, as determined by SDS-PAGE under reducing conditions
HDAC8 Activity
N/A
Tag
HDAC8 Contains A 6x histidine tag
HDAC8 Formulation
Liquid
HDAC8 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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HDAC8 family
Histone deacetylase family, HD type 1 subfamily
HDAC8 Subcellular locations
Nucleus. Cytoplasm.
HDAC8 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility.
HDAC8 Sequence
DDBJ EMBL GenBank
HDAC8 3D structure
ModBase
HDAC8 interaction
STRING
HDAC8 Proteomic
PRIDE
HDAC8 Genome annotation
Ensembl GeneID KEGG UCSC
HDAC8 Organism specific
CTD MGI
HDAC8 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
HDAC8 Gene expression
Bgee ArrayExpress Genevestigator
HDAC8 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY