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| Human Histone deacetylase 8 (aa 1-377) |
| HDAC8 Swiss Prot# | | Q9BY41 |
| HDAC8 Protein names | | Histone deacetylase 8 (HD8) (EC 3.5.1.98) |
| HDAC8 Gene names | | HDAC8 HDACL1 CDA07 |
| Organism | | Human |
| HDAC8 Entry name | | HDAC8_HUMAN |
| HDAC8 Codon optimized cDNA(gene) Clone |
| HDAC8 Cat # | | RPS0293 |
| Tag | | HDAC8 contains A 6x histidine tag |
| HDAC8 Formulation | | Liquid |
| HDAC8 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| HDAC8 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant HDAC8 Protein |
| HDAC8 Cat # | | PS0293 |
| HDAC8 Source | | recombinant |
| HDAC8 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| HDAC8 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| HDAC8 Activity | | N/A |
| Tag | | HDAC8 Contains A 6x histidine tag |
| HDAC8 Formulation | | Liquid |
| HDAC8 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant HDAC8 Products | | For pricing and availability Click Here >>> |
| HDAC8 family | | Histone deacetylase family, HD type 1 subfamily |
| HDAC8 Subcellular locations | | Nucleus. Cytoplasm. |
| HDAC8 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility. |
| HDAC8 Sequence | | DDBJ | EMBL | GenBank |
| HDAC8 3D structure | | ModBase |
| HDAC8 interaction | | STRING |
| HDAC8 Proteomic | | PRIDE |
| HDAC8 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| HDAC8 Organism specific | | CTD | MGI |
| HDAC8 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| HDAC8 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| HDAC8 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |