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Human Forkhead box protein L2 (aa 1-376)

FOXL2 Swiss Prot#

P58012

FOXL2 Protein names

Forkhead box protein L2

FOXL2 Gene names

FOXL2

Organism

Human

FOXL2 Entry name

FOXL2_HUMAN

FOXL2 Codon optimized cDNA(gene) Clone

FOXL2 Cat #

RPS0246

Tag

FOXL2 contains A 6x histidine tag

FOXL2 Formulation

Liquid

FOXL2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

FOXL2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant FOXL2 Protein

FOXL2 Cat #

PS0246

FOXL2 Source

recombinant

FOXL2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

FOXL2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

FOXL2 Activity

N/A

Tag

FOXL2 Contains A 6x histidine tag

FOXL2 Formulation

Liquid

FOXL2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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FOXL2 family

-

FOXL2 Subcellular locations

Nucleus.

FOXL2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.

FOXL2 Sequence

DDBJ

EMBL

GenBank

FOXL2 3D structure

ModBase

FOXL2 interaction

STRING

FOXL2 Proteomic

PRIDE

FOXL2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

FOXL2 Organism specific

CTD

MGI

FOXL2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

FOXL2 Gene expression

Bgee

ArrayExpress

Genevestigator

FOXL2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY