|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
||||||||||||||||||||||||||||||||||
|
|||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Human Homeobox protein ESX1 (aa 1-406) |
| ESX1L Swiss Prot# | | Q8N693 |
| ESX1L Protein names | | Homeobox protein ESX1 (Extraembryonic, spermatogenesis, homeobox 1) [Cleaved into: Homeobox protein ESX1-N; Homeobox protein ESX1-C] |
| ESX1L Gene names | | ESX1 ESX1L ESX1R |
| Organism | | Human |
| ESX1L Entry name | | ESX1_HUMAN |
| ESX1L Codon optimized cDNA(gene) Clone |
| ESX1L Cat # | | RPS0198 |
| Tag | | ESX1L contains A 6x histidine tag |
| ESX1L Formulation | | Liquid |
| ESX1L Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| ESX1L Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant ESX1L Protein |
| ESX1L Cat # | | PS0198 |
| ESX1L Source | | recombinant |
| ESX1L Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| ESX1L Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| ESX1L Activity | | N/A |
| Tag | | ESX1L Contains A 6x histidine tag |
| ESX1L Formulation | | Liquid |
| ESX1L Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant ESX1L Products | | For pricing and availability Click Here >>> |
| ESX1L family | | - |
| ESX1L Subcellular locations | | Cytoplasm. Nucleus. |
| ESX1L FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: May coordinately regulate cell cycle progression and transcription during spermatogenesis. Inhibits degradation of polyubiquitinated cyclin A and cyclin B1 and thereby arrests the cell cycle at early M phase. ESXR1-N acts as a transcriptional repressor. Binds to the sequence 5'-TAATGTTATTA-3' which is present within the first intron of the KRAS gene and inhibits its expression. ESXR1-C has the ability to inhibit cyclin turnover. |
| ESX1L Sequence | | DDBJ | EMBL | GenBank |
| ESX1L 3D structure | | ModBase |
| ESX1L interaction | | STRING |
| ESX1L Proteomic | | PRIDE |
| ESX1L Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| ESX1L Organism specific | | CTD | MGI |
| ESX1L Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| ESX1L Gene expression | | Bgee | ArrayExpress | Genevestigator |
| ESX1L Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |