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MOUSE Evolutionarily conserved signaling intermediate Toll (aa 1-435)

Sitpec Swiss Prot#

Q9QZH6

Sitpec Protein names

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein SITPEC)

Sitpec Gene names

Ecsit Sitpec

Organism

MOUSE

Sitpec Entry name

ECSIT_MOUSE

Sitpec Codon optimized cDNA(gene) Clone

Sitpec Cat #

RPS0165

Tag

Sitpec contains A 6x histidine tag

Sitpec Formulation

Liquid

Sitpec Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Sitpec Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Sitpec Protein

Sitpec Cat #

PS0165

Sitpec Source

recombinant

Sitpec Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Sitpec Purity

>90%, as determined by SDS-PAGE under reducing conditions

Sitpec Activity

N/A

Tag

Sitpec Contains A 6x histidine tag

Sitpec Formulation

Liquid

Sitpec Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Sitpec family

ECSIT family

Sitpec Subcellular locations

Cytoplasm. Nucleus. Mitochondrion.

Sitpec FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase (By similarity). Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development.

Sitpec Sequence

DDBJ

EMBL

GenBank

Sitpec 3D structure

ModBase

Sitpec interaction

STRING

Sitpec Proteomic

PRIDE

Sitpec Genome annotation

Ensembl

GeneID

KEGG

UCSC

Sitpec Organism specific

CTD

MGI

Sitpec Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Sitpec Gene expression

Bgee

ArrayExpress

Genevestigator

Sitpec Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY