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| Human Zinc finger protein DPF3 (aa 1-378) |
| BAF45C Swiss Prot# | | Q92784 |
| BAF45C Protein names | | Zinc finger protein DPF3 (Zinc finger protein cer-d4) (BRG1-associated factor 45C) (BAF45C) |
| BAF45C Gene names | | DPF3 BAF45C CERD4 |
| Organism | | Human |
| BAF45C Entry name | | DPF3_HUMAN |
| BAF45C Codon optimized cDNA(gene) Clone |
| BAF45C Cat # | | RPS0155 |
| Tag | | BAF45C contains A 6x histidine tag |
| BAF45C Formulation | | Liquid |
| BAF45C Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| BAF45C Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant BAF45C Protein |
| BAF45C Cat # | | PS0155 |
| BAF45C Source | | recombinant |
| BAF45C Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| BAF45C Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| BAF45C Activity | | N/A |
| Tag | | BAF45C Contains A 6x histidine tag |
| BAF45C Formulation | | Liquid |
| BAF45C Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant BAF45C Products | | For pricing and availability Click Here >>> |
| BAF45C family | | Requiem/DPF family |
| BAF45C Subcellular locations | | Nucleus. |
| BAF45C FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development. |
| BAF45C Sequence | | DDBJ | EMBL | GenBank |
| BAF45C 3D structure | | ModBase |
| BAF45C interaction | | STRING |
| BAF45C Proteomic | | PRIDE |
| BAF45C Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| BAF45C Organism specific | | CTD | MGI |
| BAF45C Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| BAF45C Gene expression | | Bgee | ArrayExpress | Genevestigator |
| BAF45C Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
