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Human mRNA-decapping enzyme 1A (aa 1-582)

SMIF Swiss Prot#

Q9NPI6

SMIF Protein names

mRNA-decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator)

SMIF Gene names

DCP1A SMIF

Organism

Human

SMIF Entry name

DCP1A_HUMAN

SMIF Codon optimized cDNA(gene) Clone

SMIF Cat #

RPS0125

Tag

SMIF contains A 6x histidine tag

SMIF Formulation

Liquid

SMIF Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SMIF Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SMIF Protein

SMIF Cat #

PS0125

SMIF Source

recombinant

SMIF Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SMIF Purity

>90%, as determined by SDS-PAGE under reducing conditions

SMIF Activity

N/A

Tag

SMIF Contains A 6x histidine tag

SMIF Formulation

Liquid

SMIF Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SMIF family

DCP1 family

SMIF Subcellular locations

Cytoplasm > P-body. Nucleus.

SMIF FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.

SMIF Sequence

DDBJ

EMBL

GenBank

SMIF 3D structure

ModBase

SMIF interaction

STRING

SMIF Proteomic

PRIDE

SMIF Genome annotation

Ensembl

GeneID

KEGG

UCSC

SMIF Organism specific

CTD

MGI

SMIF Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SMIF Gene expression

Bgee

ArrayExpress

Genevestigator

SMIF Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY