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Human CCAAT enhancer-binding protein beta (aa 1-345)

LAP Swiss Prot#

P17676

LAP Protein names

CCAAT/enhancer-binding protein beta (C/EBP beta) (Liver activator protein) (Nuclear factor NF-IL6) (Transcription factor 5) (TCF-5)

LAP Gene names

CEBPB LAP TCF5 PP9092

Organism

Human

LAP Entry name

CEBPB_HUMAN

LAP Codon optimized cDNA(gene) Clone

LAP Cat #

RPS0082

Tag

LAP contains A 6x histidine tag

LAP Formulation

Liquid

LAP Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

LAP Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant LAP Protein

LAP Cat #

PS0082

LAP Source

recombinant

LAP Applications

Western Blot, SDS-Page or may be used for other applications determined by user

LAP Purity

>90%, as determined by SDS-PAGE under reducing conditions

LAP Activity

N/A

Tag

LAP Contains A 6x histidine tag

LAP Formulation

Liquid

LAP Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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LAP family

BZIP family, C/EBP subfamily

LAP Subcellular locations

Nucleus.

LAP FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation (By similarity).

LAP Sequence

DDBJ

EMBL

GenBank

LAP 3D structure

ModBase

LAP interaction

STRING

LAP Proteomic

PRIDE

LAP Genome annotation

Ensembl

GeneID

KEGG

UCSC

LAP Organism specific

CTD

MGI

LAP Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

LAP Gene expression

Bgee

ArrayExpress

Genevestigator

LAP Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY