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Human Class E basic helix-loop-helix protein 22 (aa 1-381)

BHLHE22 Swiss Prot#

Q8NFJ8

BHLHE22 Protein names

Class E basic helix-loop-helix protein 22 (bHLHe22) (Class B basic helix-loop-helix protein 5) (bHLHb5) (Trinucleotide repeat-containing gene 20 protein)

BHLHE22 Gene names

BHLHE22 BHLHB5 TNRC20

Organism

Human

BHLHE22 Entry name

BHE22_HUMAN

BHLHE22 Codon optimized cDNA(gene) Clone

BHLHE22 Cat #

RPS0040

Tag

BHLHE22 contains A 6x histidine tag

BHLHE22 Formulation

Liquid

BHLHE22 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

BHLHE22 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant BHLHE22 Protein

BHLHE22 Cat #

PS0040

BHLHE22 Source

recombinant

BHLHE22 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

BHLHE22 Purity

>90%, as determined by SDS-PAGE under reducing conditions

BHLHE22 Activity

N/A

Tag

BHLHE22 Contains A 6x histidine tag

BHLHE22 Formulation

Liquid

BHLHE22 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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BHLHE22 family

-

BHLHE22 Subcellular locations

Nucleus.

BHLHE22 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA (By similarity).

BHLHE22 Sequence

DDBJ

EMBL

GenBank

BHLHE22 3D structure

ModBase

BHLHE22 interaction

STRING

BHLHE22 Proteomic

PRIDE

BHLHE22 Genome annotation

Ensembl

GeneID

KEGG

UCSC

BHLHE22 Organism specific

CTD

MGI

BHLHE22 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

BHLHE22 Gene expression

Bgee

ArrayExpress

Genevestigator

BHLHE22 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY