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Human Cysteine protease ATG4B (aa 1-393)

APG4B Swiss Prot#

Q9Y4P1

APG4B Protein names

Cysteine protease ATG4B (EC 3.4.22.-) (Autophagy-related protein 4 homolog B) (hAPG4B) (Autophagin-1) (Autophagy-related cysteine endopeptidase 1) (AUT-like 1 cysteine endopeptidase)

APG4B Gene names

ATG4B APG4B AUTL1 KIAA0943

Organism

Human

APG4B Entry name

ATG4B_HUMAN

APG4B Codon optimized cDNA(gene) Clone

APG4B Cat #

RPS0029

Tag

APG4B contains A 6x histidine tag

APG4B Formulation

Liquid

APG4B Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

APG4B Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant APG4B Protein

APG4B Cat #

PS0029

APG4B Source

recombinant

APG4B Applications

Western Blot, SDS-Page or may be used for other applications determined by user

APG4B Purity

>90%, as determined by SDS-PAGE under reducing conditions

APG4B Activity

N/A

Tag

APG4B Contains A 6x histidine tag

APG4B Formulation

Liquid

APG4B Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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APG4B family

Peptidase C54 family

APG4B Subcellular locations

Cytoplasm.

APG4B FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

APG4B Sequence

DDBJ

EMBL

GenBank

APG4B 3D structure

ModBase

APG4B interaction

STRING

APG4B Proteomic

PRIDE

APG4B Genome annotation

Ensembl

GeneID

KEGG

UCSC

APG4B Organism specific

CTD

MGI

APG4B Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

APG4B Gene expression

Bgee

ArrayExpress

Genevestigator

APG4B Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY