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SALTY Guanine nucleotide exchange factor sopE2 (aa 21-240)

STM1855 Swiss Prot#

Q7CQD4

STM1855 Protein names

Guanine nucleotide exchange factor sopE2 (Effector protein sopE2) (toxin sopE2)

STM1855 Gene names

sopE2 (STM1855)

Organism

Salmonella typhimurium

STM1855 Entry name

SOPE2_SALTY

STM1855 Codon optimized cDNA(gene) Clone

STM1855 Cat #

RPQ0148

Tag

STM1855 contains A 6x histidine tag

STM1855 Formulation

Liquid

STM1855 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

STM1855 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant STM1855 Protein

STM1855 Cat #

PQ0148

STM1855 Source

recombinant

STM1855 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

STM1855 Purity

>90%, as determined by SDS-PAGE under reducing conditions

STM1855 Activity

N/A

Tag

STM1855 Contains A 6x histidine tag

STM1855 Formulation

Liquid

STM1855 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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STM1855 family

GEF (guanine exchange factor) sopE family

STM1855 Subcellular locations

Secreted.

STM1855 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Activator for CDC42 by directly engaging this Rho GTPase and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells. Also activates NF-kB, p38 and ERK kinases, which are known to be involved in the induction of IL-8 expression. Chaperone invB is required for secretion, translocation and stabilization of intracellular levels of sopE2.

STM1855 Sequence

DDBJ

EMBL

GenBank

STM1855 3D structure

ModBase

STM1855 interaction

STRING

STM1855 Proteomic

PRIDE

STM1855 Genome annotation

Ensembl

GeneID

KEGG

UCSC

STM1855 Organism specific

CTD

MGI

STM1855 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

STM1855 Gene expression

Bgee

ArrayExpress

Genevestigator

STM1855 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY