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BPH19 Shiga-like toxin 1 subunit A (aa 1-315)

sltA Swiss Prot#

P08026

sltA Protein names

Shiga-like toxin 1 subunit A (SLT-1 A subunit) (SLT-1a) (SLT-Ia) (EC 3.2.2.22) (Verotoxin 1 subunit A) (Verocytotoxin 1 subunit A) (rRNA N-glycosidase 1)

sltA Gene names

stxA (sltA)

Organism

Enterobacteria phage H19B (Bacteriophage H19B)

sltA Entry name

STXA_BPH19

sltA Codon optimized cDNA(gene) Clone

sltA Cat #

RPQ0089

Tag

sltA contains A 6x histidine tag

sltA Formulation

Liquid

sltA Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

sltA Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant sltA Protein

sltA Cat #

PQ0089

sltA Source

recombinant

sltA Applications

Western Blot, SDS-Page or may be used for other applications determined by user

sltA Purity

>90%, as determined by SDS-PAGE under reducing conditions

sltA Activity

N/A

Tag

sltA Contains A 6x histidine tag

sltA Formulation

Liquid

sltA Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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sltA family

Ribosome-inactivating protein family

sltA Subcellular locations

Secreted.

sltA FUNCTION According to UniProtKB Swiss Prot

FUNCTION: The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subnit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits.

sltA Sequence

DDBJ

EMBL

GenBank

sltA 3D structure

ModBase

sltA interaction

STRING

sltA Proteomic

PRIDE

sltA Genome annotation

Ensembl

GeneID

KEGG

UCSC

sltA Organism specific

CTD

MGI

sltA Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

sltA Gene expression

Bgee

ArrayExpress

Genevestigator

sltA Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY