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CLOBO Botulinum neurotoxin type G (aa 61-460)

botG Swiss Prot#

Q60393

botG Protein names

Botulinum neurotoxin type G (BoNT/G) (EC 3.4.24.69) (Bontoxilysin-G) [Cleaved into: Botulinum neurotoxin G light chain; Botulinum neurotoxin G heavy chain]

botG Gene names

botG

Organism

Clostridium botulinum

botG Entry name

BXG_CLOBO

botG Codon optimized cDNA(gene) Clone

botG Cat #

RPQ0059

Tag

botG contains A 6x histidine tag

botG Formulation

Liquid

botG Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

botG Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant botG Protein

botG Cat #

PQ0059

botG Source

recombinant

botG Applications

Western Blot, SDS-Page or may be used for other applications determined by user

botG Purity

>90%, as determined by SDS-PAGE under reducing conditions

botG Activity

N/A

Tag

botG Contains A 6x histidine tag

botG Formulation

Liquid

botG Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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botG family

Peptidase M27 family

botG Subcellular locations

Secreted.

botG FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase.

botG Sequence

DDBJ

EMBL

GenBank

botG 3D structure

ModBase

botG interaction

STRING

botG Proteomic

PRIDE

botG Genome annotation

Ensembl

GeneID

KEGG

UCSC

botG Organism specific

CTD

MGI

botG Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

botG Gene expression

Bgee

ArrayExpress

Genevestigator

botG Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY