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| Rat Ephrin-A1 (aa 18-205) |
| Epgl1 Swiss Prot# | | P97553 |
| Epgl1 Protein names | | Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) |
| Epgl1 Gene names | | Efna1 (Epgl1) (Lerk1) |
| Organism | | Rat |
| Epgl1 Entry name | | EFNA1_RAT |
| Epgl1 Codon optimized cDNA(gene) Clone |
| Epgl1 Cat # | | RPU0373 |
| Tag | | Epgl1 contains A 6x histidine tag |
| Epgl1 Formulation | | Liquid |
| Epgl1 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Epgl1 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant Epgl1 Protein |
| Epgl1 Cat # | | PU0373 |
| Epgl1 Source | | recombinant |
| Epgl1 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| Epgl1 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Epgl1 Activity | | N/A |
| Tag | | Epgl1 Contains A 6x histidine tag |
| Epgl1 Formulation | | Liquid |
| Epgl1 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant Epgl1 Products | | For pricing and availability Click Here >>> |
| Epgl1 family | | Ephrin family |
| Epgl1 Subcellular locations | | Cell membrane; Lipid-anchor > GPI-anchor. Secreted. |
| Epgl1 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Plays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of embryonic neuronal growth cones (By similarity). |
| Epgl1 Sequence | | DDBJ | EMBL | GenBank |
| Epgl1 3D structure | | ModBase |
| Epgl1 interaction | | STRING |
| Epgl1 Proteomic | | PRIDE |
| Epgl1 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| Epgl1 Organism specific | | CTD | MGI |
| Epgl1 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| Epgl1 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| Epgl1 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |