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Mouse Phospholipid hydroperoxide glutathione peroxidase (aa 1-197)

Gpx4 Swiss Prot#

O70325

Gpx4 Protein names

Phospholipid hydroperoxide glutathione peroxidase, mitochondrial (PHGPx) (EC 1.11.1.12) (GPX-4)

Gpx4 Gene names

Gpx4

Organism

Mouse

Gpx4 Entry name

GPX41_MOUSE

Gpx4 Codon optimized cDNA(gene) Clone

Gpx4 Cat #

RPU0277

Tag

Gpx4 contains A 6x histidine tag

Gpx4 Formulation

Liquid

Gpx4 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Gpx4 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Gpx4 Protein

Gpx4 Cat #

PU0277

Gpx4 Source

recombinant

Gpx4 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Gpx4 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Gpx4 Activity

N/A

Tag

Gpx4 Contains A 6x histidine tag

Gpx4 Formulation

Liquid

Gpx4 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Gpx4 family

Glutathione peroxidase family

Gpx4 Subcellular locations

Mitochondrion. Cytoplasm.

Gpx4 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Protects cells against membrane lipid peroxidation and cell death. Isoform mitochondrial is required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage.

Gpx4 Sequence

DDBJ

EMBL

GenBank

Gpx4 3D structure

ModBase

Gpx4 interaction

STRING

Gpx4 Proteomic

PRIDE

Gpx4 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Gpx4 Organism specific

CTD

MGI

Gpx4 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Gpx4 Gene expression

Bgee

ArrayExpress

Genevestigator

Gpx4 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY