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Mouse Keratin type I cytoskeletal 17 (aa 1-433)

Krt1-17 Swiss Prot#

Q9QWL7

Krt1-17 Protein names

Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17)

Krt1-17 Gene names

Krt17 (Krt1-17)

Organism

Mouse

Krt1-17 Entry name

K1C17_MOUSE

Krt1-17 Codon optimized cDNA(gene) Clone

Krt1-17 Cat #

RPU0236

Tag

Krt1-17 contains A 6x histidine tag

Krt1-17 Formulation

Liquid

Krt1-17 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Krt1-17 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Krt1-17 Protein

Krt1-17 Cat #

PU0236

Krt1-17 Source

recombinant

Krt1-17 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Krt1-17 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Krt1-17 Activity

N/A

Tag

Krt1-17 Contains A 6x histidine tag

Krt1-17 Formulation

Liquid

Krt1-17 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Krt1-17 family

Intermediate filament family

Krt1-17 Subcellular locations

Cytoplasm.

Krt1-17 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation (By similarity).

Krt1-17 Sequence

DDBJ

EMBL

GenBank

Krt1-17 3D structure

ModBase

Krt1-17 interaction

STRING

Krt1-17 Proteomic

PRIDE

Krt1-17 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Krt1-17 Organism specific

CTD

MGI

Krt1-17 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Krt1-17 Gene expression

Bgee

ArrayExpress

Genevestigator

Krt1-17 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY