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Mouse Homeobox expressed in ES cells 1 (aa 1-185)

Hes-1 Swiss Prot#

Q61658

Hes-1 Protein names

Homeobox expressed in ES cells 1 (Homeobox protein ANF) (Anterior-restricted homeobox protein) (Rathke pouch homeo box)

Hes-1 Gene names

Hesx1 (Hes-1) (Rpx)

Organism

Mouse

Hes-1 Entry name

HESX1_MOUSE

Hes-1 Codon optimized cDNA(gene) Clone

Hes-1 Cat #

RPU0213

Tag

Hes-1 contains A 6x histidine tag

Hes-1 Formulation

Liquid

Hes-1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Hes-1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Hes-1 Protein

Hes-1 Cat #

PU0213

Hes-1 Source

recombinant

Hes-1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Hes-1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Hes-1 Activity

N/A

Tag

Hes-1 Contains A 6x histidine tag

Hes-1 Formulation

Liquid

Hes-1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Hes-1 family

ANF homeobox family

Hes-1 Subcellular locations

Nucleus.

Hes-1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland. Possible transcriptional repressor. Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'. HESX1 and PROP1 bind as heterodimers on this palindromic site, and, in vitro, HESX1 can antagonize PROP1 activation.

Hes-1 Sequence

DDBJ

EMBL

GenBank

Hes-1 3D structure

ModBase

Hes-1 interaction

STRING

Hes-1 Proteomic

PRIDE

Hes-1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Hes-1 Organism specific

CTD

MGI

Hes-1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Hes-1 Gene expression

Bgee

ArrayExpress

Genevestigator

Hes-1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY