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| Mouse Heart- and neural crest derivatives-expressed 2 (aa 1-217) |
| Dhand Swiss Prot# | | Q61039 |
| Dhand Protein names | | Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2) |
| Dhand Gene names | | Hand2 (Dhand) (Hed) (Thing2) |
| Organism | | Mouse |
| Dhand Entry name | | HAND2_MOUSE |
| Dhand Codon optimized cDNA(gene) Clone |
| Dhand Cat # | | RPU0205 |
| Tag | | Dhand contains A 6x histidine tag |
| Dhand Formulation | | Liquid |
| Dhand Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Dhand Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant Dhand Protein |
| Dhand Cat # | | PU0205 |
| Dhand Source | | recombinant |
| Dhand Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| Dhand Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Dhand Activity | | N/A |
| Tag | | Dhand Contains A 6x histidine tag |
| Dhand Formulation | | Liquid |
| Dhand Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant Dhand Products | | For pricing and availability Click Here >>> |
| Dhand family | | - |
| Dhand Subcellular locations | | Nucleus. |
| Dhand FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'. |
| Dhand Sequence | | DDBJ | EMBL | GenBank |
| Dhand 3D structure | | ModBase |
| Dhand interaction | | STRING |
| Dhand Proteomic | | PRIDE |
| Dhand Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| Dhand Organism specific | | CTD | MGI |
| Dhand Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| Dhand Gene expression | | Bgee | ArrayExpress | Genevestigator |
| Dhand Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |