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  • For cDNA or Recombinant Protein Search ( Input  
    Gene name, or Protein Name, or Swiss -prot Accession
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Mouse Hairy enhancer-of-split related with YRPW motif 2 (aa 1-339)
Chf1 Swiss Prot#
Q9QUS4
Chf1 Protein names
Hairy/enhancer-of-split related with YRPW motif protein 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (mHRT2) (HES-related repressor protein 2) (Protein gridlock homolog)
Chf1 Gene names
Hey2 (Chf1) (Herp) (Herp1) (Hesr2) (Hrt2)
Organism
Mouse
Chf1 Entry name
HEY2_MOUSE
Chf1 Codon optimized cDNA(gene) Clone
Chf1 Cat #
RPU0204
Tag
Chf1 contains A 6x histidine tag
Chf1 Formulation
Liquid
Chf1 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Chf1 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Chf1 Protein
Chf1 Cat #
PU0204
Chf1 Source
recombinant
Chf1 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
Chf1 Purity
>90%, as determined by SDS-PAGE under reducing conditions
Chf1 Activity
N/A
Tag
Chf1 Contains A 6x histidine tag
Chf1 Formulation
Liquid
Chf1 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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Chf1 family
HEY family
Chf1 Subcellular locations
Nucleus.
Chf1 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Transcriptional repressor which functions as a downstream effector of Notch signaling in cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY1 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3.
Chf1 Sequence
DDBJ EMBL GenBank
Chf1 3D structure
ModBase
Chf1 interaction
STRING
Chf1 Proteomic
PRIDE
Chf1 Genome annotation
Ensembl GeneID KEGG UCSC
Chf1 Organism specific
CTD MGI
Chf1 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Chf1 Gene expression
Bgee ArrayExpress Genevestigator
Chf1 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY