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Mouse Granzyme B(G H) (aa 10-247)

Ctla-1 Swiss Prot#

P04187

Ctla-1 Protein names

Granzyme B(G,H) (EC 3.4.21.79) (Cytotoxic cell protease 1) (CCP1) (CTLA-1) (Fragmentin-2)

Ctla-1 Gene names

Gzmb (Ctla-1) (Ctla1)

Organism

Mouse

Ctla-1 Entry name

GRAB_MOUSE

Ctla-1 Codon optimized cDNA(gene) Clone

Ctla-1 Cat #

RPU0200

Tag

Ctla-1 contains A 6x histidine tag

Ctla-1 Formulation

Liquid

Ctla-1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Ctla-1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Ctla-1 Protein

Ctla-1 Cat #

PU0200

Ctla-1 Source

recombinant

Ctla-1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Ctla-1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Ctla-1 Activity

N/A

Tag

Ctla-1 Contains A 6x histidine tag

Ctla-1 Formulation

Liquid

Ctla-1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Ctla-1 family

Peptidase S1 family, Granzyme subfamily

Ctla-1 Subcellular locations

Cytoplasmic granule.

Ctla-1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis (By similarity).

Ctla-1 Sequence

DDBJ

EMBL

GenBank

Ctla-1 3D structure

ModBase

Ctla-1 interaction

STRING

Ctla-1 Proteomic

PRIDE

Ctla-1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Ctla-1 Organism specific

CTD

MGI

Ctla-1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Ctla-1 Gene expression

Bgee

ArrayExpress

Genevestigator

Ctla-1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY