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Mouse Docking protein 4 (aa 1-325)

Dok4 Swiss Prot#

Q99KE3

Dok4 Protein names

Docking protein 4 (Downstream of tyrosine kinase 4)

Dok4 Gene names

Dok4

Organism

Mouse

Dok4 Entry name

DOK4_MOUSE

Dok4 Codon optimized cDNA(gene) Clone

Dok4 Cat #

RPU0173

Tag

Dok4 contains A 6x histidine tag

Dok4 Formulation

Liquid

Dok4 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Dok4 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Dok4 Protein

Dok4 Cat #

PU0173

Dok4 Source

recombinant

Dok4 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Dok4 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Dok4 Activity

N/A

Tag

Dok4 Contains A 6x histidine tag

Dok4 Formulation

Liquid

Dok4 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Dok4 family

DOK family, Type B subfamily

Dok4 Subcellular locations

-

Dok4 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells (By similarity).

Dok4 Sequence

DDBJ

EMBL

GenBank

Dok4 3D structure

ModBase

Dok4 interaction

STRING

Dok4 Proteomic

PRIDE

Dok4 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Dok4 Organism specific

CTD

MGI

Dok4 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Dok4 Gene expression

Bgee

ArrayExpress

Genevestigator

Dok4 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY