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Mouse Cyclin-dependent kinase inhibitor 1B (aa 1-197)

Cdkn1b Swiss Prot#

P46414

Cdkn1b Protein names

Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1)

Cdkn1b Gene names

Cdkn1b

Organism

Mouse

Cdkn1b Entry name

CDN1B_MOUSE

Cdkn1b Codon optimized cDNA(gene) Clone

Cdkn1b Cat #

RPU0165

Tag

Cdkn1b contains A 6x histidine tag

Cdkn1b Formulation

Liquid

Cdkn1b Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Cdkn1b Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Cdkn1b Protein

Cdkn1b Cat #

PU0165

Cdkn1b Source

recombinant

Cdkn1b Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Cdkn1b Purity

>90%, as determined by SDS-PAGE under reducing conditions

Cdkn1b Activity

N/A

Tag

Cdkn1b Contains A 6x histidine tag

Cdkn1b Formulation

Liquid

Cdkn1b Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Cdkn1b family

CDI family

Cdkn1b Subcellular locations

Nucleus. Cytoplasm. Endosome.

Cdkn1b FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of cyclin D-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

Cdkn1b Sequence

DDBJ

EMBL

GenBank

Cdkn1b 3D structure

ModBase

Cdkn1b interaction

STRING

Cdkn1b Proteomic

PRIDE

Cdkn1b Genome annotation

Ensembl

GeneID

KEGG

UCSC

Cdkn1b Organism specific

CTD

MGI

Cdkn1b Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Cdkn1b Gene expression

Bgee

ArrayExpress

Genevestigator

Cdkn1b Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY