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Human Tumor necrosis factor receptor superfamily 10D (aa 56-386)

DCR2 Swiss Prot#

Q9UBN6

DCR2 Protein names

Tumor necrosis factor receptor superfamily member 10D (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD antigen CD264)

DCR2 Gene names

TNFRSF10D (DCR2) (TRAILR4) (TRUNDD) (UNQ251/PRO288)

Organism

Human

DCR2 Entry name

TR10D_HUMAN

DCR2 Codon optimized cDNA(gene) Clone

DCR2 Cat #

RPU0117

Tag

DCR2 contains A 6x histidine tag

DCR2 Formulation

Liquid

DCR2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

DCR2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant DCR2 Protein

DCR2 Cat #

PU0117

DCR2 Source

recombinant

DCR2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

DCR2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

DCR2 Activity

N/A

Tag

DCR2 Contains A 6x histidine tag

DCR2 Formulation

Liquid

DCR2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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DCR2 family

-

DCR2 Subcellular locations

Membrane; Single-pass type I membrane protein.

DCR2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.

DCR2 Sequence

DDBJ

EMBL

GenBank

DCR2 3D structure

ModBase

DCR2 interaction

STRING

DCR2 Proteomic

PRIDE

DCR2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

DCR2 Organism specific

CTD

MGI

DCR2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

DCR2 Gene expression

Bgee

ArrayExpress

Genevestigator

DCR2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY