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Human Indian hedgehog protein (aa 28-411)

IHH Swiss Prot#

Q14623

IHH Protein names

Indian hedgehog protein (IHH) (HHG-2) [Cleaved into: Indian hedgehog protein N-product; Indian hedgehog protein C-product]

IHH Gene names

IHH

Organism

Human

IHH Entry name

IHH_HUMAN

IHH Codon optimized cDNA(gene) Clone

IHH Cat #

RPU0059

Tag

IHH contains A 6x histidine tag

IHH Formulation

Liquid

IHH Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

IHH Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant IHH Protein

IHH Cat #

PU0059

IHH Source

recombinant

IHH Applications

Western Blot, SDS-Page or may be used for other applications determined by user

IHH Purity

>90%, as determined by SDS-PAGE under reducing conditions

IHH Activity

N/A

Tag

IHH Contains A 6x histidine tag

IHH Formulation

Liquid

IHH Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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IHH family

Hedgehog family

IHH Subcellular locations

Cell membrane; Lipid-anchor; Extracellular side. Secreted > extracellular space.

IHH FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity).

IHH Sequence

DDBJ

EMBL

GenBank

IHH 3D structure

ModBase

IHH interaction

STRING

IHH Proteomic

PRIDE

IHH Genome annotation

Ensembl

GeneID

KEGG

UCSC

IHH Organism specific

CTD

MGI

IHH Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

IHH Gene expression

Bgee

ArrayExpress

Genevestigator

IHH Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY