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Human Double C2-like domain-containing protein alpha (aa 1-400)

DOC2A Swiss Prot#

Q14183

DOC2A Protein names

Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2)

DOC2A Gene names

DOC2A

Organism

Human

DOC2A Entry name

DOC2A_HUMAN

DOC2A Codon optimized cDNA(gene) Clone

DOC2A Cat #

RPU0036

Tag

DOC2A contains A 6x histidine tag

DOC2A Formulation

Liquid

DOC2A Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

DOC2A Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant DOC2A Protein

DOC2A Cat #

PU0036

DOC2A Source

recombinant

DOC2A Applications

Western Blot, SDS-Page or may be used for other applications determined by user

DOC2A Purity

>90%, as determined by SDS-PAGE under reducing conditions

DOC2A Activity

N/A

Tag

DOC2A Contains A 6x histidine tag

DOC2A Formulation

Liquid

DOC2A Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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DOC2A family

-

DOC2A Subcellular locations

Lysosome. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane; Peripheral membrane protein. Cell junction > synapse > synaptosome.

DOC2A FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.

DOC2A Sequence

DDBJ

EMBL

GenBank

DOC2A 3D structure

ModBase

DOC2A interaction

STRING

DOC2A Proteomic

PRIDE

DOC2A Genome annotation

Ensembl

GeneID

KEGG

UCSC

DOC2A Organism specific

CTD

MGI

DOC2A Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

DOC2A Gene expression

Bgee

ArrayExpress

Genevestigator

DOC2A Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY