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| Mouse Dickkopf-related protein 3 (aa 23-349) |
| Dkk3 Swiss Prot# | | Q9QUN9 |
| Dkk3 Protein names | | Dickkopf-related protein 3 (Dickkopf-3) (Dkk-3) (mDkk-3) |
| Dkk3 Gene names | | Dkk3 |
| Organism | | Mus musculus (Mouse) |
| Dkk3 Entry name | | DKK3_MOUSE |
| Dkk3 Codon optimized cDNA(gene) Clone |
| Dkk3 Cat # | | RPM0422 |
| Tag | | Dkk3 contains A 6x histidine tag |
| Dkk3 Formulation | | Liquid |
| Dkk3 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Dkk3 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant Dkk3 Protein |
| Dkk3 Cat # | | PM0422 |
| Dkk3 Source | | recombinant |
| Dkk3 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| Dkk3 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Dkk3 Activity | | N/A |
| Tag | | Dkk3 Contains A 6x histidine tag |
| Dkk3 Formulation | | Liquid |
| Dkk3 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant Dkk3 Products | | For pricing and availability Click Here >>> |
| Dkk3 family | | Dickkopf family |
| Dkk3 Subcellular locations | | Secreted. |
| Dkk3 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer's disease (By similarity). |
| Dkk3 Sequence | | DDBJ | EMBL | GenBank |
| Dkk3 3D structure | | ModBase |
| Dkk3 interaction | | STRING |
| Dkk3 Proteomic | | PRIDE |
| Dkk3 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| Dkk3 Organism specific | | CTD | MGI |
| Dkk3 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| Dkk3 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| Dkk3 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |