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Mouse Death-associated protein kinase 3 (aa 13-275)

Zipk Swiss Prot#

O54784

Zipk Protein names

Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (ZIP-kinase)

Zipk Gene names

Dapk3 (Zipk)

Organism

Mus musculus (Mouse)

Zipk Entry name

DAPK3_MOUSE

Zipk Codon optimized cDNA(gene) Clone

Zipk Cat #

RPM0398

Tag

Zipk contains A 6x histidine tag

Zipk Formulation

Liquid

Zipk Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Zipk Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Zipk Protein

Zipk Cat #

PM0398

Zipk Source

recombinant

Zipk Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Zipk Purity

>90%, as determined by SDS-PAGE under reducing conditions

Zipk Activity

N/A

Tag

Zipk Contains A 6x histidine tag

Zipk Formulation

Liquid

Zipk Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Zipk family

Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily

Zipk Subcellular locations

Nucleus. Cytoplasm. Chromosome > centromere.

Zipk FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Serine/threonine kinase which acts as a positive regulator of apoptosis. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. Regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. Involved in the formation of promyelocytic leukemia protein nuclear body (PML-NB), one of many subnuclear domains in the eukaryotic cell nucleus, and which is involved in oncogenesis and viral infection (By similarity).

Zipk Sequence

DDBJ

EMBL

GenBank

Zipk 3D structure

ModBase

Zipk interaction

STRING

Zipk Proteomic

PRIDE

Zipk Genome annotation

Ensembl

GeneID

KEGG

UCSC

Zipk Organism specific

CTD

MGI

Zipk Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Zipk Gene expression

Bgee

ArrayExpress

Genevestigator

Zipk Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY