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Mouse Nuclear receptor subfamily 2 group C member 1 (aa 1-590)

Tr2 Swiss Prot#

Q505F1

Tr2 Protein names

Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2) (mTR2)

Tr2 Gene names

Nr2c1 (Tr2) (Tr2-11)

Organism

Mus musculus (Mouse)

Tr2 Entry name

NR2C1_MOUSE

Tr2 Codon optimized cDNA(gene) Clone

Tr2 Cat #

RPM0390

Tag

Tr2 contains A 6x histidine tag

Tr2 Formulation

Liquid

Tr2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Tr2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Tr2 Protein

Tr2 Cat #

PM0390

Tr2 Source

recombinant

Tr2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Tr2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Tr2 Activity

N/A

Tag

Tr2 Contains A 6x histidine tag

Tr2 Formulation

Liquid

Tr2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Tr2 family

Nuclear hormone receptor family, NR2 subfamily

Tr2 Subcellular locations

Nucleus. Nucleus > PML body.

Tr2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes including ESR1 and RARB. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences (By similarity). Also activator of OCT4 gene expression. Plays a fundamental role in early embryogenesis and regulates embryonic stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.

Tr2 Sequence

DDBJ

EMBL

GenBank

Tr2 3D structure

ModBase

Tr2 interaction

STRING

Tr2 Proteomic

PRIDE

Tr2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Tr2 Organism specific

CTD

MGI

Tr2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Tr2 Gene expression

Bgee

ArrayExpress

Genevestigator

Tr2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY