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Mouse Nuclear receptor ROR-alpha (aa 1-523)

Nr1f1 Swiss Prot#

P51448

Nr1f1 Protein names

Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha) (Nuclear receptor subfamily 1 group F member 1)

Nr1f1 Gene names

Rora (Nr1f1) (Rzra)

Organism

Mus musculus (Mouse)

Nr1f1 Entry name

RORA_MOUSE

Nr1f1 Codon optimized cDNA(gene) Clone

Nr1f1 Cat #

RPM0385

Tag

Nr1f1 contains A 6x histidine tag

Nr1f1 Formulation

Liquid

Nr1f1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Nr1f1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Nr1f1 Protein

Nr1f1 Cat #

PM0385

Nr1f1 Source

recombinant

Nr1f1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Nr1f1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Nr1f1 Activity

N/A

Tag

Nr1f1 Contains A 6x histidine tag

Nr1f1 Formulation

Liquid

Nr1f1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Nr1f1 family

Nuclear hormone receptor family, NR1 subfamily

Nr1f1 Subcellular locations

Nucleus.

Nr1f1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Orphan nuclear receptor. Binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. This isomer binds to the consensus sequence 5'-[AT][TA]A[AT][CGT]TAGGTCA-3'. Regulates a number of genes involved in lipid metabolism such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma, in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3, in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1. Possible receptor for cholesterol or one of its derivatives (By similarity).

Nr1f1 Sequence

DDBJ

EMBL

GenBank

Nr1f1 3D structure

ModBase

Nr1f1 interaction

STRING

Nr1f1 Proteomic

PRIDE

Nr1f1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Nr1f1 Organism specific

CTD

MGI

Nr1f1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Nr1f1 Gene expression

Bgee

ArrayExpress

Genevestigator

Nr1f1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY