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Mouse Myocyte-specific enhancer factor 2C (aa 1-474)
Mef2c Swiss Prot#
Q8CFN5
Mef2c Protein names
Myocyte-specific enhancer factor 2C
Mef2c Gene names
Mef2c
Organism
Mus musculus (Mouse)
Mef2c Entry name
MEF2C_MOUSE
Mef2c Codon optimized cDNA(gene) Clone
Mef2c Cat #
RPM0378
Tag
Mef2c contains A 6x histidine tag
Mef2c Formulation
Liquid
Mef2c Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Mef2c Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Mef2c Protein
Mef2c Cat #
PM0378
Mef2c Source
recombinant
Mef2c Applications
Western Blot, SDS-Page or may be used for other applications determined by user
Mef2c Purity
>90%, as determined by SDS-PAGE under reducing conditions
Mef2c Activity
N/A
Tag
Mef2c Contains A 6x histidine tag
Mef2c Formulation
Liquid
Mef2c Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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Mef2c family
MEF2 family
Mef2c Subcellular locations
Nucleus.
Mef2c FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. May also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1, isoform 2 and isoform 5 (By similarity). Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells.
Mef2c Sequence
DDBJ EMBL GenBank
Mef2c 3D structure
ModBase
Mef2c interaction
STRING
Mef2c Proteomic
PRIDE
Mef2c Genome annotation
Ensembl GeneID KEGG UCSC
Mef2c Organism specific
CTD MGI
Mef2c Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Mef2c Gene expression
Bgee ArrayExpress Genevestigator
Mef2c Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY