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| Mouse Myocyte-specific enhancer factor 2C (aa 1-474) |
| Mef2c Swiss Prot# | | Q8CFN5 |
| Mef2c Protein names | | Myocyte-specific enhancer factor 2C |
| Mef2c Gene names | | Mef2c |
| Organism | | Mus musculus (Mouse) |
| Mef2c Entry name | | MEF2C_MOUSE |
| Mef2c Codon optimized cDNA(gene) Clone |
| Mef2c Cat # | | RPM0378 |
| Tag | | Mef2c contains A 6x histidine tag |
| Mef2c Formulation | | Liquid |
| Mef2c Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Mef2c Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant Mef2c Protein |
| Mef2c Cat # | | PM0378 |
| Mef2c Source | | recombinant |
| Mef2c Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| Mef2c Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Mef2c Activity | | N/A |
| Tag | | Mef2c Contains A 6x histidine tag |
| Mef2c Formulation | | Liquid |
| Mef2c Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant Mef2c Products | | For pricing and availability Click Here >>> |
| Mef2c family | | MEF2 family |
| Mef2c Subcellular locations | | Nucleus. |
| Mef2c FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. May also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1, isoform 2 and isoform 5 (By similarity). Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. |
| Mef2c Sequence | | DDBJ | EMBL | GenBank |
| Mef2c 3D structure | | ModBase |
| Mef2c interaction | | STRING |
| Mef2c Proteomic | | PRIDE |
| Mef2c Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| Mef2c Organism specific | | CTD | MGI |
| Mef2c Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| Mef2c Gene expression | | Bgee | ArrayExpress | Genevestigator |
| Mef2c Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |