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Mouse Protein arginine N-methyltransferase 1 (aa 1-371)

Hrmt1l2 Swiss Prot#

Q9JIF0

Hrmt1l2 Protein names

Protein arginine N-methyltransferase 1 (EC 2.1.1.-)

Hrmt1l2 Gene names

Prmt1 (Hrmt1l2) (Mrmt1)

Organism

Mus musculus (Mouse)

Hrmt1l2 Entry name

ANM1_MOUSE

Hrmt1l2 Codon optimized cDNA(gene) Clone

Hrmt1l2 Cat #

RPM0360

Tag

Hrmt1l2 contains A 6x histidine tag

Hrmt1l2 Formulation

Liquid

Hrmt1l2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Hrmt1l2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Hrmt1l2 Protein

Hrmt1l2 Cat #

PM0360

Hrmt1l2 Source

recombinant

Hrmt1l2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Hrmt1l2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Hrmt1l2 Activity

N/A

Tag

Hrmt1l2 Contains A 6x histidine tag

Hrmt1l2 Formulation

Liquid

Hrmt1l2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Hrmt1l2 family

Protein arginine N-methyltransferase family

Hrmt1l2 Subcellular locations

Nucleus. Cytoplasm > cytosol.

Hrmt1l2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation. Together with dimethylated PIAS1, represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. May be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and act as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway.

Hrmt1l2 Sequence

DDBJ

EMBL

GenBank

Hrmt1l2 3D structure

ModBase

Hrmt1l2 interaction

STRING

Hrmt1l2 Proteomic

PRIDE

Hrmt1l2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Hrmt1l2 Organism specific

CTD

MGI

Hrmt1l2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Hrmt1l2 Gene expression

Bgee

ArrayExpress

Genevestigator

Hrmt1l2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY