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Human S-phase kinase-associated protein 1 (aa 2-163)

EMC19 Swiss Prot#

P63208

EMC19 Protein names

S-phase kinase-associated protein 1 (Cyclin A/CDK2-associated protein p19) (p19skp1) (p19A) (RNA polymerase II elongation factor-like protein) (Organ of Corti protein 2) (OCP-2) (OCP-II) (Transcription elongation factor B) (SIII)

EMC19 Gene names

SKP1 (EMC19) (OCP2) (SKP1A) (TCEB1L)

Organism

Homo sapiens (Human)

EMC19 Entry name

SKP1_HUMAN

EMC19 Codon optimized cDNA(gene) Clone

EMC19 Cat #

RPM0190

Tag

EMC19 contains A 6x histidine tag

EMC19 Formulation

Liquid

EMC19 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

EMC19 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant EMC19 Protein

EMC19 Cat #

PM0190

EMC19 Source

recombinant

EMC19 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

EMC19 Purity

>90%, as determined by SDS-PAGE under reducing conditions

EMC19 Activity

N/A

Tag

EMC19 Contains A 6x histidine tag

EMC19 Formulation

Liquid

EMC19 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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EMC19 family

SKP1 family

EMC19 Subcellular locations

-

EMC19 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110.

EMC19 Sequence

DDBJ

EMBL

GenBank

EMC19 3D structure

ModBase

EMC19 interaction

STRING

EMC19 Proteomic

PRIDE

EMC19 Genome annotation

Ensembl

GeneID

KEGG

UCSC

EMC19 Organism specific

CTD

MGI

EMC19 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

EMC19 Gene expression

Bgee

ArrayExpress

Genevestigator

EMC19 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY