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Human Secreted frizzled-related protein 3 (aa 33-325)

FIZ Swiss Prot#

Q92765

FIZ Protein names

Secreted frizzled-related protein 3 (sFRP-3) (Frizzled-related protein 1) (FrzB-1) (Frezzled) (Fritz)

FIZ Gene names

FRZB (FIZ) (FRE) (FRP) (FRZB1) (SFRP3)

Organism

Homo sapiens (Human)

FIZ Entry name

SFRP3_HUMAN

FIZ Codon optimized cDNA(gene) Clone

FIZ Cat #

RPM0166

Tag

FIZ contains A 6x histidine tag

FIZ Formulation

Liquid

FIZ Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

FIZ Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant FIZ Protein

FIZ Cat #

PM0166

FIZ Source

recombinant

FIZ Applications

Western Blot, SDS-Page or may be used for other applications determined by user

FIZ Purity

>90%, as determined by SDS-PAGE under reducing conditions

FIZ Activity

N/A

Tag

FIZ Contains A 6x histidine tag

FIZ Formulation

Liquid

FIZ Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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FIZ family

Secreted frizzled-related protein (sFRP) family

FIZ Subcellular locations

Secreted.

FIZ FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

FIZ Sequence

DDBJ

EMBL

GenBank

FIZ 3D structure

ModBase

FIZ interaction

STRING

FIZ Proteomic

PRIDE

FIZ Genome annotation

Ensembl

GeneID

KEGG

UCSC

FIZ Organism specific

CTD

MGI

FIZ Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

FIZ Gene expression

Bgee

ArrayExpress

Genevestigator

FIZ Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY