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Human Histone deacetylase 2 (aa 1-488)

HDAC2 Swiss Prot#

Q92769

HDAC2 Protein names

Histone deacetylase 2 (HD2) (EC 3.5.1.98)

HDAC2 Gene names

HDAC2

Organism

Homo sapiens (Human)

HDAC2 Entry name

HDAC2_HUMAN

HDAC2 Codon optimized cDNA(gene) Clone

HDAC2 Cat #

RPM0121

Tag

HDAC2 contains A 6x histidine tag

HDAC2 Formulation

Liquid

HDAC2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

HDAC2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant HDAC2 Protein

HDAC2 Cat #

PM0121

HDAC2 Source

recombinant

HDAC2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

HDAC2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

HDAC2 Activity

N/A

Tag

HDAC2 Contains A 6x histidine tag

HDAC2 Formulation

Liquid

HDAC2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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HDAC2 family

Histone deacetylase family, HD type 1 subfamily

HDAC2 Subcellular locations

Nucleus.

HDAC2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity).; FUNCTION: Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity.

HDAC2 Sequence

DDBJ

EMBL

GenBank

HDAC2 3D structure

ModBase

HDAC2 interaction

STRING

HDAC2 Proteomic

PRIDE

HDAC2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

HDAC2 Organism specific

CTD

MGI

HDAC2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

HDAC2 Gene expression

Bgee

ArrayExpress

Genevestigator

HDAC2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY