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Human Transcription factor SOX-17 (aa 1-414)

SOX17 Swiss Prot#

Q9H6I2

SOX17 Protein names

Transcription factor SOX-17

SOX17 Gene names

SOX17

Organism

Homo sapiens (Human)

SOX17 Entry name

SOX17_HUMAN

SOX17 Codon optimized cDNA(gene) Clone

SOX17 Cat #

RPM0112

Tag

SOX17 contains A 6x histidine tag

SOX17 Formulation

Liquid

SOX17 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SOX17 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SOX17 Protein

SOX17 Cat #

PM0112

SOX17 Source

recombinant

SOX17 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SOX17 Purity

>90%, as determined by SDS-PAGE under reducing conditions

SOX17 Activity

N/A

Tag

SOX17 Contains A 6x histidine tag

SOX17 Formulation

Liquid

SOX17 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SOX17 family

-

SOX17 Subcellular locations

Nucleus.

SOX17 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells (By similarity).

SOX17 Sequence

DDBJ

EMBL

GenBank

SOX17 3D structure

ModBase

SOX17 interaction

STRING

SOX17 Proteomic

PRIDE

SOX17 Genome annotation

Ensembl

GeneID

KEGG

UCSC

SOX17 Organism specific

CTD

MGI

SOX17 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SOX17 Gene expression

Bgee

ArrayExpress

Genevestigator

SOX17 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY