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Human Transcription factor PU.1 (aa 1-270)

SPI1 Swiss Prot#

P17947

SPI1 Protein names

Transcription factor PU.1 (31 kDa-transforming protein)

SPI1 Gene names

SPI1

Organism

Homo sapiens (Human)

SPI1 Entry name

SPI1_HUMAN

SPI1 Codon optimized cDNA(gene) Clone

SPI1 Cat #

RPM0098

Tag

SPI1 contains A 6x histidine tag

SPI1 Formulation

Liquid

SPI1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SPI1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SPI1 Protein

SPI1 Cat #

PM0098

SPI1 Source

recombinant

SPI1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SPI1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

SPI1 Activity

N/A

Tag

SPI1 Contains A 6x histidine tag

SPI1 Formulation

Liquid

SPI1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SPI1 family

ETS family

SPI1 Subcellular locations

Nucleus.

SPI1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing (By similarity).

SPI1 Sequence

DDBJ

EMBL

GenBank

SPI1 3D structure

ModBase

SPI1 interaction

STRING

SPI1 Proteomic

PRIDE

SPI1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

SPI1 Organism specific

CTD

MGI

SPI1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SPI1 Gene expression

Bgee

ArrayExpress

Genevestigator

SPI1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY