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Human CBF1-interacting corepressor (aa 1-450)

CIR Swiss Prot#

Q86X95

CIR Protein names

CBF1-interacting corepressor (Recepin)

CIR Gene names

CIR

Organism

Homo sapiens (Human)

CIR Entry name

CIR1_HUMAN

CIR Codon optimized cDNA(gene) Clone

CIR Cat #

RPM0084

Tag

CIR contains A 6x histidine tag

CIR Formulation

Liquid

CIR Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CIR Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CIR Protein

CIR Cat #

PM0084

CIR Source

recombinant

CIR Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CIR Purity

>90%, as determined by SDS-PAGE under reducing conditions

CIR Activity

N/A

Tag

CIR Contains A 6x histidine tag

CIR Formulation

Liquid

CIR Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CIR family

-

CIR Subcellular locations

Nucleus speckle.

CIR FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription.

CIR Sequence

DDBJ

EMBL

GenBank

CIR 3D structure

ModBase

CIR interaction

STRING

CIR Proteomic

PRIDE

CIR Genome annotation

Ensembl

GeneID

KEGG

UCSC

CIR Organism specific

CTD

MGI

CIR Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CIR Gene expression

Bgee

ArrayExpress

Genevestigator

CIR Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY