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Human Selenoprotein S (aa 1-189)

VIMP Swiss Prot#

Q9BQE4

VIMP Protein names

Selenoprotein S (SelS) (VCP-interacting membrane protein)

VIMP Gene names

SELS (VIMP) (AD-015) (SBBI8)

Organism

Homo sapiens (Human)

VIMP Entry name

SELS_HUMAN

VIMP Codon optimized cDNA(gene) Clone

VIMP Cat #

RPM0073

Tag

VIMP contains A 6x histidine tag

VIMP Formulation

Liquid

VIMP Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

VIMP Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant VIMP Protein

VIMP Cat #

PM0073

VIMP Source

recombinant

VIMP Applications

Western Blot, SDS-Page or may be used for other applications determined by user

VIMP Purity

>90%, as determined by SDS-PAGE under reducing conditions

VIMP Activity

N/A

Tag

VIMP Contains A 6x histidine tag

VIMP Formulation

Liquid

VIMP Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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VIMP family

Selenoprotein S family

VIMP Subcellular locations

Endoplasmic reticulum membrane; Single-pass membrane protein.

VIMP FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.

VIMP Sequence

DDBJ

EMBL

GenBank

VIMP 3D structure

ModBase

VIMP interaction

STRING

VIMP Proteomic

PRIDE

VIMP Genome annotation

Ensembl

GeneID

KEGG

UCSC

VIMP Organism specific

CTD

MGI

VIMP Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

VIMP Gene expression

Bgee

ArrayExpress

Genevestigator

VIMP Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY