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Human TRAF family member-associated NF-kappa-B activator (aa 1-425)

ITRAF Swiss Prot#

Q92844

ITRAF Protein names

TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF)

ITRAF Gene names

TANK (ITRAF) (TRAF2)

Organism

Homo sapiens (Human)

ITRAF Entry name

TANK_HUMAN

ITRAF Codon optimized cDNA(gene) Clone

ITRAF Cat #

RPM0032

Tag

ITRAF contains A 6x histidine tag

ITRAF Formulation

Liquid

ITRAF Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ITRAF Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ITRAF Protein

ITRAF Cat #

PM0032

ITRAF Source

recombinant

ITRAF Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ITRAF Purity

>90%, as determined by SDS-PAGE under reducing conditions

ITRAF Activity

N/A

Tag

ITRAF Contains A 6x histidine tag

ITRAF Formulation

Liquid

ITRAF Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ITRAF family

-

ITRAF Subcellular locations

Cytoplasm.

ITRAF FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Acts as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity.

ITRAF Sequence

DDBJ

EMBL

GenBank

ITRAF 3D structure

ModBase

ITRAF interaction

STRING

ITRAF Proteomic

PRIDE

ITRAF Genome annotation

Ensembl

GeneID

KEGG

UCSC

ITRAF Organism specific

CTD

MGI

ITRAF Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ITRAF Gene expression

Bgee

ArrayExpress

Genevestigator

ITRAF Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY