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Human RNA-binding protein 38 (aa 1-239)

RNPC1 Swiss Prot#

Q9H0Z9

RNPC1 Protein names

RNA-binding protein 38 (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (HSRNASEB) (ssDNA-binding protein SEB4) (CLL-associated antigen KW-5)

RNPC1 Gene names

RBM38 (RNPC1) (SEB4)

Organism

Homo sapiens (Human)

RNPC1 Entry name

RBM38_HUMAN

RNPC1 Codon optimized cDNA(gene) Clone

RNPC1 Cat #

RPM0010

Tag

RNPC1 contains A 6x histidine tag

RNPC1 Formulation

Liquid

RNPC1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

RNPC1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant RNPC1 Protein

RNPC1 Cat #

PM0010

RNPC1 Source

recombinant

RNPC1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

RNPC1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

RNPC1 Activity

N/A

Tag

RNPC1 Contains A 6x histidine tag

RNPC1 Formulation

Liquid

RNPC1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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RNPC1 family

RBM38 family

RNPC1 Subcellular locations

Cytoplasm > cytosol. Nucleus.

RNPC1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.

RNPC1 Sequence

DDBJ

EMBL

GenBank

RNPC1 3D structure

ModBase

RNPC1 interaction

STRING

RNPC1 Proteomic

PRIDE

RNPC1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

RNPC1 Organism specific

CTD

MGI

RNPC1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

RNPC1 Gene expression

Bgee

ArrayExpress

Genevestigator

RNPC1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY