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Human Transforming growth factor beta-1-induced transcript 1 (aa 1-461)

ARA55 Swiss Prot#

O43294

ARA55 Protein names

Transforming growth factor beta-1-induced transcript 1 protein (Hydrogen peroxide-inducible clone 5 protein) (Hic-5) (Androgen receptor-associated protein of 55 kDa)

ARA55 Gene names

TGFB1I1 (ARA55)

Organism

Homo sapiens (Human)

ARA55 Entry name

TGFI1_HUMAN

ARA55 Codon optimized cDNA(gene) Clone

ARA55 Cat #

RPM0001

Tag

ARA55 contains A 6x histidine tag

ARA55 Formulation

Liquid

ARA55 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ARA55 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ARA55 Protein

ARA55 Cat #

PM0001

ARA55 Source

recombinant

ARA55 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ARA55 Purity

>90%, as determined by SDS-PAGE under reducing conditions

ARA55 Activity

N/A

Tag

ARA55 Contains A 6x histidine tag

ARA55 Formulation

Liquid

ARA55 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ARA55 family

Paxillin family

ARA55 Subcellular locations

Cell junction > focal adhesion. Nucleus matrix. Cytoplasm > cytoskeleton.

ARA55 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. May play a role in the processes of cell growth, proliferation, migration, differentiation and senescence. May have a zinc-dependent DNA-binding activity.

ARA55 Sequence

DDBJ

EMBL

GenBank

ARA55 3D structure

ModBase

ARA55 interaction

STRING

ARA55 Proteomic

PRIDE

ARA55 Genome annotation

Ensembl

GeneID

KEGG

UCSC

ARA55 Organism specific

CTD

MGI

ARA55 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ARA55 Gene expression

Bgee

ArrayExpress

Genevestigator

ARA55 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY