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Mouse CDK5 and ABL1 enzyme substrate 1 (aa 1-568)

Cables Swiss Prot#

Q9ESJ1

Cables Protein names

CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1)

Cables Gene names

Cables1 (Cables)

Organism

Mouse

Cables Entry name

CABL1_MOUSE

Cables Codon optimized cDNA(gene) Clone

Cables Cat #

RPX0218

Tag

Cables contains A 6x histidine tag

Cables Formulation

Liquid

Cables Storage

Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Cables Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Cables Protein

t Cables Cat #

PX0218

Cables Source

t protein

t Cables Applications

Western Blot, SDS-Page or may be used for other applications determined by user

t Cables Purity

>90%, as determined by SDS-PAGE under reducing conditions

t Cables Activity

N/A

t Tag

t Cables Contains A 6x histidine tag

t Cables Formulation

Liquid

t Cables Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Cables family

Cyclin family

Cables Subcellular locations

Nucleus. Cytoplasm. Cell projection > growth cone.

Cables FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity).

Cables Sequence

DDBJ

EMBL

GenBank

Cables 3D structure

ModBase

Cables interaction

STRING

Cables Proteomic

PRIDE

Cables Genome annotation

Ensembl

GeneID

KEGG

UCSC

Cables Organism specific

CTD

MGI

Cables Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Cables Gene expression

Bgee

ArrayExpress

Genevestigator

Cables Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY