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Mouse BTB POZ domain-containing protein KCTD11 (aa 1-232)

Ren Swiss Prot#

Q8K485

Ren Protein names

BTB/POZ domain-containing protein KCTD11

Ren Gene names

Kctd11 (Ren)

Organism

Mouse

Ren Entry name

KCD11_MOUSE

Ren Codon optimized cDNA(gene) Clone

Ren Cat #

RPX0204

Tag

Ren contains A 6x histidine tag

Ren Formulation

Liquid

Ren Storage

Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Ren Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Ren Protein

t Ren Cat #

PX0204

Ren Source

t protein

t Ren Applications

Western Blot, SDS-Page or may be used for other applications determined by user

t Ren Purity

>90%, as determined by SDS-PAGE under reducing conditions

t Ren Activity

N/A

t Tag

t Ren Contains A 6x histidine tag

t Ren Formulation

Liquid

t Ren Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Ren family

-

Ren Subcellular locations

-

Ren FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Play a role as a marker and a regulator of neuronal differentiation; Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and NGFB/nerve growth factor. Induces apoptosis, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B. Plays a role as a tumor repressor and inhibits cell growth and tumorigenicity of medulloblastoma (MDB). Functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcrition factor GLI1, thus maintaining cerebellar granule cells in undifferentiated state. When knock-down, Hedgehog antagonism is impaired and proliferation of granule cells is sustained. Activates the caspase cascade.

Ren Sequence

DDBJ

EMBL

GenBank

Ren 3D structure

ModBase

Ren interaction

STRING

Ren Proteomic

PRIDE

Ren Genome annotation

Ensembl

GeneID

KEGG

UCSC

Ren Organism specific

CTD

MGI

Ren Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Ren Gene expression

Bgee

ArrayExpress

Genevestigator

Ren Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY